During the Ebola virus disease outbreak in West Africa, an advisory panel to the World Health Organization (WHO) argued that it can be ethically appropriate to offer individual patients experimental interventions on an emergency basis outside clinical trials provided that certain conditions are met (MEURI framework) In the spirit of finding common ground in the area of using unproven interventions during public health emergencies, we (1) provide a brief introduction to MEURI, (2) compare Webb et al.'s proposal to the existing MEURI framework, and (3) outline key areas where the use and allocation of unproven interventions can be enhanced.