UNIGE document Scientific Article
previous document  unige:144381  next document
add to browser collection
Title

Linking alpha oscillations, attention and inhibitory control in adult ADHD with EEG neurofeedback

Authors
Published in NeuroImage: Clinical. 2020, vol. 25, p. 102145
Abstract Abnormal patterns of electrical oscillatory activity have been repeatedly described in adult ADHD. In particular, the alpha rhythm (8-12 Hz), known to be modulated during attention, has previously been considered as candidate biomarker for ADHD. In the present study, we asked adult ADHD patients to self-regulate their own alpha rhythm using neurofeedback (NFB), in order to examine the modulation of alpha oscillations on attentional performance and brain plasticity. Twenty-five adult ADHD patients and 22 healthy controls underwent a 64-channel EEG-recording at resting-state and during a Go/NoGo task, before and after a 30 min-NFB session designed to reduce (desynchronize) the power of the alpha rhythm. Alpha power was compared across conditions and groups, and the effects of NFB were statistically assessed by comparing behavioral and EEG measures pre-to-post NFB. Firstly, we found that relative alpha power was attenuated in our ADHD cohort compared to control subjects at baseline and across experimental conditions, suggesting a signature of cortical hyper-activation. Both groups demonstrated a significant and targeted reduction of alpha power during NFB. Interestingly, we observed a post-NFB increase in resting-state alpha (i.e. rebound) in the ADHD group, which restored alpha power towards levels of the normal population. Importantly, the degree of post-NFB alpha normalization during the Go/NoGo task correlated with individual improvements in motor inhibition (i.e. reduced commission errors) only in the ADHD group. Overall, our findings offer novel supporting evidence implicating alpha oscillations in inhibitory control, as well as their potential role in the homeostatic regulation of cortical excitatory/inhibitory balance.
Identifiers
PMID: 31911342
Full text
Article (Published version) (1.8 MB) - public document Free access
Supplemental data (42 Kb) - public document Free access
Structures
Research groups Thérapeutiques des Troubles de l'Humeur et Anxieux (689)
NCCR Synapsy
Groupe Dayer Alexandre (Formation du circuit cortical) (875)
Project FNS: NCCR Synapsy 51NF40-185897
Citation
(ISO format)
DEIBER IBANEZ, Marie-Pierre et al. Linking alpha oscillations, attention and inhibitory control in adult ADHD with EEG neurofeedback. In: NeuroImage: Clinical, 2020, vol. 25, p. 102145. doi: 10.1016/j.nicl.2019.102145 https://archive-ouverte.unige.ch/unige:144381

68 hits

33 downloads

Update

Deposited on : 2020-11-09

Export document
Format :
Citation style :