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Scientific article
Open access
English

Haploidentical transplantation is associated with better overall survival when compared to single cord blood transplantation: an EBMT-Eurocord study of acute leukemia patients conditioned with thiotepa, busulfan, and fludarabine

Published inJournal of Hematology & Oncology, vol. 11, no. 1, 110
Publication date2018
Abstract

Thiotepa-busulfan-fludarabine (TBF) is a widely used conditioning regimen in single umbilical cord blood transplantation (SUCBT). More recently, it was introduced in the setting of non-T cell depleted haploidentical stem cell transplantation (NTD-Haplo). Whether TBF based conditioning provides additional benefit in transplantation from a particular alternative donor type remains to be established.

Keywords
  • Adult
  • Aged
  • Busulfan/pharmacology/therapeutic use
  • Cord Blood Stem Cell Transplantation/methods/mortality
  • Female
  • Humans
  • Leukemia, Myeloid, Acute/pathology/therapy
  • Male
  • Middle Aged
  • Retrospective Studies
  • Survival Rate
  • Thiotepa/pharmacology/therapeutic use
  • Transplantation Conditioning/methods/mortality
  • Transplantation, Haploidentical/methods/mortality
  • Vidarabine/analogs & derivatives/pharmacology/therapeutic use
  • Young Adult
Affiliation Not a UNIGE publication
Citation (ISO format)
GIANNOTTI, Federica et al. Haploidentical transplantation is associated with better overall survival when compared to single cord blood transplantation: an EBMT-Eurocord study of acute leukemia patients conditioned with thiotepa, busulfan, and fludarabine. In: Journal of Hematology & Oncology, 2018, vol. 11, n° 1, p. 110. doi: 10.1186/s13045-018-0655-8
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Article (Published version)
Identifiers
ISSN of the journal1756-8722
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