Management of the dentoalveolar effects of tongue hypertrophy in patients with Duchenne muscular dystrophy: a pilot study

Antonarakis, Gregory; Morel, Catherine; Kiliaridis, Stavros

doi:10.1016/j.nmd.2019.11.009

Scientific article

English

Management of the dentoalveolar effects of tongue hypertrophy in patients with Duchenne muscular dystrophy: a pilot study

Contributors

Antonarakis, Gregory

; Morel, Catherine; Kiliaridis, Stavros

Published in

Neuromuscular Disorders, vol. 30, no. 2, p. 105-110

Publication date

2020

Abstract

Subjects affected by Duchenne muscular dystrophy (DMD) develop severe malocclusions with the progression of the disease, due to changes in orofacial musculature and function, including tongue hypertrophy. We aimed to evaluate the benefits of maintaining mandibular interarch width with the help of a simple fixed orthodontic appliance. Three adolescent DMD boys were selected consecutively to receive a passive rigid mandibular lingual arch, and followed for 4-5 years. An untreated age-matched control group was chosen and followed for a similar period. Study casts were obtained at baseline and after follow-up. Outcomes measured were overjet, overbite, maxillary and mandibular intermolar widths, mandibular arch depth, molar relationships, and the presence of lateral crossbites and anterior or lateral openbites. Changes in measurements obtained between the two time points were compared in each age-matched pair. There was a clinically important increase in the mandibular intermolar width in the non-treated children ranging from 2.5 mm to 9 mm, but not in those treated. Malocclusions generally deteriorated in untreated children while they remained stable in treated children. The use of a rigid mandibular lingual arch in boys with DMD can help slow down the rapid deterioration of the developing malocclusions that accompanies the progression of the disease.

UNIGE affiliation entities

Faculté de médecine / Section de médecine dentaire / Département de réhabilitation oro-faciale / Division d'orthodontie

UNIGE research groups

Groupe Kiliaridis Stavros (médecine dentaire) (239)

Citation (ISO format)

ANTONARAKIS, Gregory, MOREL, Catherine, KILIARIDIS, Stavros. Management of the dentoalveolar effects of tongue hypertrophy in patients with Duchenne muscular dystrophy: a pilot study. In: Neuromuscular Disorders, 2020, vol. 30, n° 2, p. 105–110. doi: 10.1016/j.nmd.2019.11.009

Article (Published version)

Identifiers

PID : unige:144115
DOI : 10.1016/j.nmd.2019.11.009
PMID : 32001146

Journal ISSN

0960-8966

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Creation

22/10/2020 18:16:00

First validation

22/10/2020 18:16:00

Update

15/03/2023 22:56:48

Status update

15/03/2023 22:56:48

Last indexation

31/10/2024 20:12:27

Management of the dentoalveolar effects of tongue hypertrophy in patients with Duchenne muscular dystrophy: a pilot study

Contributors

Published in

Publication date

Abstract

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

Main files (1)

Identifiers

Journal ISSN

Technical informations

Creation

First validation

Update

Status update

Last indexation