An unusual thrombus location in a Heartmate 3TM device with fatal outcome

Banfi, Carlo; Rigamonti, Fabio; Ahmadov, Kamran; Meyer, Philippe; Hachulla-Lemaire, Anne-Lise; Craviari, Cecilia; Fontana, Pierre; Bendjelid, Karim; Giraud, Raphaël

doi:10.1177/0267659119890218

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Title		An unusual thrombus location in a Heartmate 3TM device with fatal outcome
Authors		Banfi, Carlo Rigamonti, Fabio Ahmadov, Kamran Meyer, Philippe Hachulla-Lemaire, Anne-Lise Craviari, Cecilia Fontana, Pierre Bendjelid, Karim Giraud, Raphaël show all authors [1 - 9]
Published in		Perfusion. 2020, vol. 35, no. 5, p. 442-446
Abstract		Even if the HeartMate 3TM left ventricular assist device is associated with excellent outcomes, complications, such as pump thrombosis continue to affect patients on hemodynamic support. We report the history of a 68-year-old man who underwent implantation of an HeartMate 3TM as a bridge to transplantation. Nineteen months later, he developed signs of heart failure leading to cardiogenic shock. Neither clinical examination nor parameters from the device allowed a clear-cut diagnosis. Only surgical exploration revealed the presence of clots between the polyethylene terephthalate (Dacron®) and polytetrafluoroethylene tubes. This constitutes a weakness of this device for which we propose to the manufacturer for minimal modifications to overcome the problem.
Keywords		HeartMate 3TM — Adverse events — Cardiogenic shock and thrombolysis — Left ventricular assist devices (LVAD) — Pump thrombosis
Identifiers		DOI: 10.1177/0267659119890218 PMID: 31814521
Full text		Article (Published version) (361 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine Faculté de médecine / Section de médecine clinique / Département de chirurgie Faculté de médecine / Section de médecine clinique / Département d'anesthésiologie, pharmacologie, soins intensifs et urgences Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research groups		Geneva Platelet Group (13) Groupe de recherche en hémodynamique (913)
Citation (ISO format)		BANFI, Carlo et al. An unusual thrombus location in a Heartmate 3TM device with fatal outcome. In: Perfusion, 2020, vol. 35, n° 5, p. 442-446. doi: 10.1177/0267659119890218 https://archive-ouverte.unige.ch/unige:143376