Scientific article

English

A longitudinal study highlights shared aspects of the transcriptomic response to cardiogenic and septic shock

ContributorsBraga, Daniele; Barcella, Matteo; Herpain, Antoine; Aletti, Federico; Kistler, Erik B; Bollen Pinto, Bernardo

; Bendjelid, Karim

; Barlassina, Cristina

Published inCritical Care, vol. 23, no. 1, 414

Publication date2019

Abstract

Septic shock (SS) and cardiogenic shock (CS) are two types of circulatory shock with a different etiology. Several studies have described the molecular alterations in SS patients, whereas the molecular factors involved in CS have been poorly investigated. We aimed to assess in the whole blood of CS and SS patients, using septic patients without shock (SC) as controls, transcriptomic modifications that occur over 1 week after ICU admission and are common to the two types of shock.

Keywords

Cardiogenic shock
Circulatory shock
Critical illness
Immunoglobulin
PRR
RNA-Seq
Septic shock

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département d'anesthésiologie, pharmacologie, soins intensifs et urgences

Research groups

Groupe de recherche en hémodynamique (913)

Citation (ISO format)

BRAGA, Daniele et al. A longitudinal study highlights shared aspects of the transcriptomic response to cardiogenic and septic shock. In: Critical Care, 2019, vol. 23, n° 1, p. 414. doi: 10.1186/s13054-019-2670-8

Article (Published version)

Identifiers

PID : unige:143224
DOI : 10.1186/s13054-019-2670-8
PMID : 31856860

Commercial URLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921511/

Journal ISSN1364-8535

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Creation12/08/2020 15:47:00

First validation12/08/2020 15:47:00

Update time27/06/2024 08:59:46

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