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Synergies of VEGF inhibition and photodynamic therapy in the treatment of age-related macular degeneration |
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Published in | Investigative ophthalmology & visual science. 2007, vol. 48, no. 4, p. 1767-72 | |
Abstract | Photodynamic therapy (PDT) and the administration of compounds acting against vascular endothelial growth factor (anti-VEGF) are approved for the treatment of choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). Experimental evidence that the combined use of both treatment options may improve therapeutic outcome is presented. | |
Keywords | Animals — Chick Embryo — Chorioallantoic Membrane/blood supply/drug effects — Disease Models, Animal — Drug Synergism — Fluorescein Angiography — Humans — Liposomes — Macular Degeneration/drug therapy — Microscopy, Fluorescence — Nanoparticles — Neovascularization, Physiologic/drug effects — Photochemotherapy — Photosensitizing Agents/therapeutic use — Porphyrins/therapeutic use — Recombinant Proteins/therapeutic use — Vascular Endothelial Growth Factor A/antagonists & inhibitors — Vascular Endothelial Growth Factor Receptor-1/therapeutic use | |
Identifiers | DOI: 10.1167/iovs.06-1224 PMID: 17389510 | |
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Citation (ISO format) | ZULUAGA, Maria-Fernanda et al. Synergies of VEGF inhibition and photodynamic therapy in the treatment of age-related macular degeneration. In: Investigative ophthalmology & visual science, 2007, vol. 48, n° 4, p. 1767-72. doi: 10.1167/iovs.06-1224 https://archive-ouverte.unige.ch/unige:14307 |