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Title

Synergies of VEGF inhibition and photodynamic therapy in the treatment of age-related macular degeneration
Authors
Zuluaga, Maria-Fernanda
Mailhos, Carolina
Robinson, Gregory
Shima, David T.
Gurny, Robert
Lange, Norbert
Published in Investigative Ophthalmology & Visual Science. 2007, vol. 48, no. 4, p. 1767-72
Abstract Photodynamic therapy (PDT) and the administration of compounds acting against vascular endothelial growth factor (anti-VEGF) are approved for the treatment of choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). Experimental evidence that the combined use of both treatment options may improve therapeutic outcome is presented.
Keywords Animals — Chick Embryo — Chorioallantoic Membrane/blood supply/drug effects — Disease Models, Animal — Drug Synergism — Fluorescein Angiography — Humans — Liposomes — Macular Degeneration/drug therapy — Microscopy, Fluorescence — Nanoparticles — Neovascularization, Physiologic/drug effects — Photochemotherapy — Photosensitizing Agents/therapeutic use — Porphyrins/therapeutic use — Recombinant Proteins/therapeutic use — Vascular Endothelial Growth Factor A/antagonists & inhibitors — Vascular Endothelial Growth Factor Receptor-1/therapeutic use
Identifiers
PMID: 17389510
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Structures
Faculté des sciences / Section des sciences pharmaceutiques
Citation
(ISO format) 		ZULUAGA, Maria-Fernanda et al. Synergies of VEGF inhibition and photodynamic therapy in the treatment of age-related macular degeneration. In: Investigative Ophthalmology & Visual Science, 2007, vol. 48, n° 4, p. 1767-72. doi: 10.1167/iovs.06-1224 https://archive-ouverte.unige.ch/unige:14307

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Deposited on : 2011-02-01

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