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Quantification of perineural invasion focus after radical prostatectomy could improve predictive power of recurrence

ContributorsWu, Shulin; Xie, Ling; Lin, Sharron X; Wirth, Grégory Johann; Lu, Min; Zhang, Yifen; Blute, Michael L; Dahl, Douglas M; Wu, Chin-Lee
Published inHuman Pathology, vol. 104, p. 96-104
Publication date2020
Abstract

Perineural invasion (PNI) after radical prostatectomy (RP) is a common feature of prostate cancer (PCa) and has been associated with unfavorable tumor characteristics. However, its prognostic relevance is controversial. In this study, we evaluated the impact of both PNI status (PNI+ vs PNI-) and quantified number of PNI focus on the long-term prognosis of biochemical recurrence (BCR) after RP.

Keywords
  • focus
  • perineural invasion
  • prognosis
  • prostate cancer
  • prostatectomy
  • quantification
  • recurrence.
Affiliation entities
Research groups
Citation (ISO format)
WU, Shulin et al. Quantification of perineural invasion focus after radical prostatectomy could improve predictive power of recurrence. In: Human Pathology, 2020, vol. 104, p. 96–104. doi: 10.1016/j.humpath.2020.07.005
Main files (2)
Article (Accepted version)
accessLevelPublic CC BY-NC-ND
Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN0046-8177
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365downloads

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Creation19/08/2020 15:59:00
First validation19/08/2020 15:59:00
Update15/03/2023 22:45:21
Status update15/03/2023 22:45:20
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