Quantification of perineural invasion focus after radical prostatectomy could improve predictive power of recurrence

Wu, Shulin; Xie, Ling; Lin, Sharron X; Wirth, Grégory Johann; Lu, Min; Zhang, Yifen; Blute, Michael L; Dahl, Douglas M; Wu, Chin-Lee

doi:10.1016/j.humpath.2020.07.005

Scientific article

English

Quantification of perineural invasion focus after radical prostatectomy could improve predictive power of recurrence

ContributorsWu, Shulin; Xie, Ling; Lin, Sharron X; Wirth, Grégory Johann; Lu, Min; Zhang, Yifen; Blute, Michael L; Dahl, Douglas M; Wu, Chin-Lee

Published inHuman Pathology, vol. 104, p. 96-104

Publication date2020

Abstract

Perineural invasion (PNI) after radical prostatectomy (RP) is a common feature of prostate cancer (PCa) and has been associated with unfavorable tumor characteristics. However, its prognostic relevance is controversial. In this study, we evaluated the impact of both PNI status (PNI+ vs PNI-) and quantified number of PNI focus on the long-term prognosis of biochemical recurrence (BCR) after RP.

Keywords

focus
perineural invasion
prognosis
prostate cancer
prostatectomy
quantification
recurrence.

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de chirurgie

Research groups

Groupe Iselin Christophe (urologie) (106)

Citation (ISO format)

WU, Shulin et al. Quantification of perineural invasion focus after radical prostatectomy could improve predictive power of recurrence. In: Human Pathology, 2020, vol. 104, p. 96–104. doi: 10.1016/j.humpath.2020.07.005

Article (Accepted version)

CC BY-NC-ND

Article (Published version)

Identifiers

PID : unige:142944
DOI : 10.1016/j.humpath.2020.07.005
PMID : 32673683

Journal ISSN0046-8177

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Creation19/08/2020 17:59:00

First validation19/08/2020 17:59:00

Update time15/03/2023 23:45:21

Status update15/03/2023 23:45:20

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Quantification of perineural invasion focus after radical prostatectomy could improve predictive power of recurrence

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