en
Scientific article
English

Quantitative imaging of clathrin-mediated endocytosis

Published inCurrent Opinion in Cell Biology, vol. 53, p. 105-110
Publication date2018
Abstract

Clathrin-mediated endocytosis is a process by which eukaryotic cells bend a small region of their plasma membrane to form a transport vesicle that carries specific cargo molecules into the cell. Endocytosis controls the composition of the plasma membrane, imports nutrients and regulates many signalling pathways. The roles of most of the proteins involved in endocytosis have been thoroughly characterised. However, how these proteins cooperate in the cell to drive the endocytic process is not well understood. Microscopy methods have been instrumental in describing the dynamics and the molecular mechanism of endocytosis. Here, we will review the challenges and the recent advances in visualising the endocytic machinery and we will reflect on how the integration of current imaging technologies can lead us toward a quantitative understanding of the molecular mechanisms of endocytosis.

Citation (ISO format)
PICCO, Andrea, KAKSONEN, Marko. Quantitative imaging of clathrin-mediated endocytosis. In: Current Opinion in Cell Biology, 2018, vol. 53, p. 105–110. doi: 10.1016/j.ceb.2018.06.005
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0955-0674
243views
0downloads

Technical informations

Creation09/22/2020 10:31:00 AM
First validation09/22/2020 10:31:00 AM
Update time03/15/2023 10:38:24 PM
Status update03/15/2023 10:38:23 PM
Last indexation01/17/2024 10:56:15 AM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack