UNIGE document Doctoral Thesis
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Title

Microparticles, nanocarriers and fractional laser ablation: formulation and physical enhancement strategies to increase cutaneous and ungual drug bioavailability
Author
Gou, Si
Director
Kalia, Yogeshvar
Defense Thèse de doctorat : Univ. Genève, 2020 - Sc. Vie 51 - 2020/05/08
Abstract Dermatological conditions affect more than 50 % of the world’s population. Although topical delivery is considered superior to systemic administration for the treatment of local diseases, the efficacy of the current topical therapies is limited due to the intrinsic barrier function of skin and the nail. The results of different studies carried out during this research project have comprehensively demonstrated that the utilization of formulation (eg. hydrogel, microparticles and micelles) and physical enhancement strategies (eg. fractional laser ablation), as well as the combination of different techniques, can be used to improve topical drug delivery into skin and nails and thereby offer new approaches for more effective therapies.
Identifiers
URN: urn:nbn:ch:unige-1413763
Full text
Thesis (4.5 MB) - private document Private access (until 2022-03-08)
Structures
Faculté des sciences / Section des sciences pharmaceutiques
Citation
(ISO format) 		GOU, Si. Microparticles, nanocarriers and fractional laser ablation: formulation and physical enhancement strategies to increase cutaneous and ungual drug bioavailability. Université de Genève. Thèse, 2020. doi: 10.13097/archive-ouverte/unige:141376 https://archive-ouverte.unige.ch/unige:141376

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Deposited on : 2020-09-16

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