Scientific article

The Enantiomers of Trinorbornane and Derivatives Thereof

Published inHelvetica Chimica Acta, vol. 103, no. 3
Publication date2020

Herein, we report the synthesis of the enantiomers of trinorbornane, a tetracyclic saturated hydrocarbon with the chemical formula C11H16. The preparation of these rigid carbon scaffolds was enabled by the successful chiral separation of its tricyclic precursor, thus allowing the enantiomers to be synthesized through a reductive radical cyclization reaction. Assignment of the absolute conformation of the enantiomers was achieved through VCD experiments. Further, we report an alternative cyclization procedure providing access to hydroxyl and phenyl sulfone functionalized trinorbornanes.

Citation (ISO format)
DELARUE BIZZINI, Lorenzo, BUERGI, Thomas, MAYOR, Marcel. The Enantiomers of Trinorbornane and Derivatives Thereof. In: Helvetica Chimica Acta, 2020, vol. 103, n° 3. doi: 10.1002/hlca.202000019
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Article (Published version)
ISSN of the journal0018-019X

Technical informations

Creation09/03/2020 12:12:00 PM
First validation09/03/2020 12:12:00 PM
Update time03/15/2023 10:31:50 PM
Status update03/15/2023 10:31:49 PM
Last indexation08/30/2023 11:25:18 PM
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