en
Scientific article
Open access
English

Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay

Published inAlzheimer's & Dementia, vol. 15, no. 11, p. 1478-1488
Publication date2019
Abstract

Plasma proteins have been widely studied as candidate biomarkers to predict brain amyloid deposition to increase recruitment efficiency in secondary prevention clinical trials for Alzheimer's disease. Most such biomarker studies are targeted to specific proteins or are biased toward high abundant proteins.

Keywords
  • Amyloid β
  • Causal relationship
  • Plasma proteomics
  • Replication
  • SOMAscan assay
  • Tau.
Funding
  • European Commission - European Medical Information Framework [115372]
Citation (ISO format)
SHI, Liu et al. Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay. In: Alzheimer’s & Dementia, 2019, vol. 15, n° 11, p. 1478–1488. doi: 10.1016/j.jalz.2019.06.4951
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Article (Published version)
Identifiers
ISSN of the journal1552-5260
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119downloads

Technical informations

Creation07/10/2020 2:10:00 PM
First validation07/10/2020 2:10:00 PM
Update time03/15/2023 10:30:51 PM
Status update03/15/2023 10:30:48 PM
Last indexation02/12/2024 11:54:44 AM
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