Scientific article
OA Policy
English

Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay

Published inAlzheimer's & Dementia, vol. 15, no. 11, p. 1478-1488
Publication date2019
Abstract

Plasma proteins have been widely studied as candidate biomarkers to predict brain amyloid deposition to increase recruitment efficiency in secondary prevention clinical trials for Alzheimer's disease. Most such biomarker studies are targeted to specific proteins or are biased toward high abundant proteins.

Keywords
  • Amyloid β
  • Causal relationship
  • Plasma proteomics
  • Replication
  • SOMAscan assay
  • Tau.
Funding
  • European Commission - European Medical Information Framework [115372]
Citation (ISO format)
SHI, Liu et al. Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay. In: Alzheimer’s & Dementia, 2019, vol. 15, n° 11, p. 1478–1488. doi: 10.1016/j.jalz.2019.06.4951
Main files (1)
Article (Published version)
Identifiers
Journal ISSN1552-5260
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198downloads

Technical informations

Creation10/07/2020 14:10:00
First validation10/07/2020 14:10:00
Update time15/03/2023 22:30:51
Status update15/03/2023 22:30:48
Last indexation31/10/2024 19:34:18
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