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Title

Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay

Authors
Shi, Liu
Westwood, Sarah
Baird, Alison L
Winchester, Laura
Dobricic, Valerija
Kilpert, Fabian
Hong, Shengjun
Franke, Andre
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Published in Alzheimer's & Dementia. 2019, vol. 15, no. 11, p. 1478-1488
Abstract Plasma proteins have been widely studied as candidate biomarkers to predict brain amyloid deposition to increase recruitment efficiency in secondary prevention clinical trials for Alzheimer's disease. Most such biomarker studies are targeted to specific proteins or are biased toward high abundant proteins.
Keywords Amyloid βCausal relationshipPlasma proteomicsReplicationSOMAscan assayTau.
Identifiers
PMID: 31495601
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Structures
Research group Troubles de mémoire et maladie d'Alzeimer (935)
Project
European Commission: EMIF
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SHI, Liu et al. Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay. In: Alzheimer's & Dementia, 2019, vol. 15, n° 11, p. 1478-1488. doi: 10.1016/j.jalz.2019.06.4951 https://archive-ouverte.unige.ch/unige:140834

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Deposited on : 2020-09-06

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