Treatment of acyclovir-resistant herpetic ulceration with topical foscarnet and antiviral sensitivity analysis

Pechère, M; Wunderli, W; Toutous Trellu, Laurence Marie; Harms, M; Saura, J H; Krischer, J

doi:10.1159/000018014

Scientific article

Case report

English

Treatment of acyclovir-resistant herpetic ulceration with topical foscarnet and antiviral sensitivity analysis

ContributorsPechère, M; Wunderli, W; Toutous Trellu, Laurence Marie; Harms, M; Saura, J H; Krischer, J

Published inDermatology, vol. 197, no. 3, p. 278-280

Publication date1998

Abstract

Herpes simplex virus (HSV) can produce persistent mucocutaneous disease in patients with the acquired immunodeficiency syndrome (AIDS). In this case report, we evaluate the efficacy, safety and viral resistance after topical foscarnet in severe genital ulceration due to acyclovir-resistant HSV-2.

Keywords

Acyclovir/pharmacology
Administration
Topical
Antiviral Agents/administration & dosage/pharmacology/therapeutic use
Drug Resistance
Microbial
Female
Foscarnet/administration & dosage/therapeutic use
Genital Diseases
Female/drug therapy/pathology/virology
Herpes Genitalis/drug therapy/pathology/virology
Herpes Simplex/drug therapy
Herpesvirus 2
Human/drug effects/isolation & purification
Humans
Microbial Sensitivity Tests
Middle Aged
Skin Ulcer/drug therapy/pathology/virology

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

Mécanismes des pathologies de l'inflammation cutanée (919)

Citation (ISO format)

PECHÈRE, M et al. Treatment of acyclovir-resistant herpetic ulceration with topical foscarnet and antiviral sensitivity analysis. In: Dermatology, 1998, vol. 197, n° 3, p. 278–280. doi: 10.1159/000018014

Article (Published version)

Identifiers

PID : unige:140061
DOI : 10.1159/000018014
PMID : 9812037

ISSN of the journal1018-8665

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Treatment of acyclovir-resistant herpetic ulceration with topical foscarnet and antiviral sensitivity analysis

Herpes simplex virus (HSV) can produce persistent mucocutaneous disease in patients with the acquired immunodeficiency syndrome (AIDS). In this case report, we evaluate the efficacy, safety and viral resistance after topical foscarnet in severe genital ulceration due to acyclovir-resistant HSV-2.

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