Scientific article

Towards quantitative small-animal imaging on hybrid PET/CT and PET/MRI systems

Published inClinical and Translational Imaging, vol. 8, no. 4, p. 243-263
Publication date2020

Over the past two decades, innovations in small-animal positron emission tomography (PET) have reached an impressive level, which has brought countless opportunities to explore the major puzzles in biomedical research. It is a given that pairing information coming from different imaging modalities renders unprecedented knowledge and provides a great insight into various facets of biological systems, such as anatomy, function, physiology, and metabolism in animal models of human diseases, which are difficult to be beaten by standalone PET scanners. The development of bimodal and tri-modal imaging platforms with advanced software solutions dedicated for quantitative studies in small-animals has spurred academic and industrial interest. However, it is undisputed that the potential success of these scanners in filling the translational gap between human and animal findings, hinges to a great extent upon optimization and standardization of relevant parameters and acquisition protocols, which is often overlooked.

  • Preclinical imaging
  • Image reconstruction
  • Kinetic modeling
  • Multi-modality
  • Quantification
  • Swiss National Science Foundation - SNRF 320030_176052
Citation (ISO format)
AMIRRASHEDI, Mahsa, ZAIDI, Habib, AY, Mohammad Reza. Towards quantitative small-animal imaging on hybrid PET/CT and PET/MRI systems. In: Clinical and Translational Imaging, 2020, vol. 8, n° 4, p. 243–263. doi: 10.1007/s40336-020-00376-y
Main files (1)
Article (Published version)
ISSN of the journal2281-5872

Technical informations

Creation07/24/2020 12:32:00 PM
First validation07/24/2020 12:32:00 PM
Update time03/15/2023 10:24:45 PM
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