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Title

RB137 and RB138 antibodies recognize human cathelicidin LL37 by ELISA

Authors
Palazzo, Raffaella
Pietraforte, Immacolata
Lande, Roberto
Published in Antibody Reports. 2020, vol. 3, no. 3, p. e188
Collection OAP Journals - Antibody Reports
Abstract LL37 is a cationic antimicrobial peptide (AMP), which can undergo post-translational modifications (PTM), such as citrullination and carbamylation. We demonstrate here that recombinant antibodies RB137 and RB138 are specific for native LL37 and do not recognize modified LL37 (citrullinated and carbamylated). They thus represent tools to assess the presence of native, unmodified LL37 in body fluids by ELISA.
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Research group Phagocytose (140)
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PALAZZO, Raffaella et al. RB137 and RB138 antibodies recognize human cathelicidin LL37 by ELISA. In: Antibody Reports, 2020, vol. 3, n° 3, p. e188. doi: 10.24450/journals/abrep.2020.e188 https://archive-ouverte.unige.ch/unige:138774

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Deposited on : 2020-07-31

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