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Title

IL-18 as a biomarker linking systemic juvenile idiopathic arthritis and macrophage activation syndrome

Authors
Yasin, Shima
Fall, Ndate
Brown, Rachel A
Henderlight, Maggie
Canna, Scott W
Grom, Alexei A
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Published in Rheumatology. 2020, vol. 59, no. 2, p. 361-366
Abstract Systemic juvenile idiopathic arthritis (sJIA) is a childhood arthritis with features of autoinflammation and high risk of macrophage activation syndrome (MAS). IL-18 has been shown to have key roles in sJIA and MAS. We aimed to examine IL-18 levels in sJIA in relation to disease activity and history of MAS and other disease biomarkers namely S100 proteins and CXCL9.
Keywords Arthritis, Juvenile/blood/diagnosisBiomarkers/bloodChemokine CXCL9/bloodFemaleFerritins/bloodHumansInterleukin-18/bloodMacrophage Activation Syndrome/blood/diagnosisMaleS100 Proteins/bloodSeverity of Illness Index
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PMID: 31326996
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Other version: https://academic.oup.com/rheumatology/article/59/2/361/5536572
Structures
Research group Mécanisme de l'inflammation articulaire (44)
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YASIN, Shima et al. IL-18 as a biomarker linking systemic juvenile idiopathic arthritis and macrophage activation syndrome. In: Rheumatology, 2020, vol. 59, n° 2, p. 361-366. doi: 10.1093/rheumatology/kez282 https://archive-ouverte.unige.ch/unige:138640

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Deposited on : 2020-07-30

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