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Title

Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study

Authors
van Maurik, Ingrid S
Vos, Stephanie J
Bos, Isabelle
Bouwman, Femke H
Teunissen, Charlotte E
Scheltens, Philip
Barkhof, Frederik
Frolich, Lutz
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Published in The Lancet Neurology. 2019, vol. 18, no. 11, p. 1034-1044
Abstract Biomarker-based risk predictions of dementia in people with mild cognitive impairment are highly relevant for care planning and to select patients for treatment when disease-modifying drugs become available. We aimed to establish robust prediction models of disease progression in people at risk of dementia.
Keywords AgedAged, 80 and overAlzheimer Disease/cerebrospinal fluid/epidemiology/pathologyAmyloid beta-Peptides/cerebrospinal fluidBiomarkers/cerebrospinal fluidCognitive Dysfunction/cerebrospinal fluid/pathologyDisease ProgressionEurope/epidemiologyFemaleFollow-Up StudiesHippocampus/pathologyHumansKaplan-Meier EstimateMagnetic Resonance ImagingMaleMiddle AgedMulticenter Studies as Topic/statistics & numerical dataNerve DegenerationNeuroimagingNorth America/epidemiologyOrgan SizePeptide Fragments/cerebrospinal fluidPhosphorylationPrognosisProportional Hazards ModelsProtein Processing, Post-Translationaltau Proteins/cerebrospinal fluid/chemistry
Identifiers
PMID: 31526625
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Article (Published version) (563 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Appendix (881 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Other version: https://www.sciencedirect.com/science/article/pii/S1474442219302832
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Research group Troubles de mémoire et maladie d'Alzeimer (935)
Citation
(ISO format)
VAN MAURIK, Ingrid S et al. Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study. In: The Lancet Neurology, 2019, vol. 18, n° 11, p. 1034-1044. doi: 10.1016/S1474-4422(19)30283-2 https://archive-ouverte.unige.ch/unige:138511

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Deposited on : 2020-07-20

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