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An isolated venous sac as a novel site for cell therapy in diabetes mellitus

Kakabadze, Zurab
Shanava, Koba
Ricordi, Camillo
Shapiro, A M James
Gupta, Sanjeev
Published in Transplantation. 2012, vol. 94, no. 4, p. 319-24
Abstract Transplanting pancreatic islets is of significant interest for type 1 diabetes mellitus. After intraportal injection of islets, inferior engraftment and eventual loss of transplanted islets constitute major limitations. Therefore, alternative approaches will be helpful. Here, we evaluated in animals whether an isolated venous sac would support survival of transplanted islets, along with correction of hyperglycemia.
Keywords AnimalsDiabetes Mellitus, Experimental/surgeryGlucose Tolerance TestIslets of Langerhans Transplantation/methods/mortalityMalePortal Vein/physiopathologyRatsRats, Inbred LewSaphenous Vein/physiopathologyStreptozocin
PMID: 22814331
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Research group Création de tissus par bio-ingénieurie et régénération d'organes (1021)
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KAKABADZE, Zurab et al. An isolated venous sac as a novel site for cell therapy in diabetes mellitus. In: Transplantation, 2012, vol. 94, n° 4, p. 319-24. doi: 10.1097/TP.0b013e31825e4a83

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Deposited on : 2020-07-14

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