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Scientific article
English

An isolated venous sac as a novel site for cell therapy in diabetes mellitus

Published inTransplantation, vol. 94, no. 4, p. 319-324
Publication date2012
Abstract

Transplanting pancreatic islets is of significant interest for type 1 diabetes mellitus. After intraportal injection of islets, inferior engraftment and eventual loss of transplanted islets constitute major limitations. Therefore, alternative approaches will be helpful. Here, we evaluated in animals whether an isolated venous sac would support survival of transplanted islets, along with correction of hyperglycemia.

Keywords
  • Animals
  • Diabetes Mellitus, Experimental/surgery
  • Glucose Tolerance Test
  • Islets of Langerhans Transplantation/methods/mortality
  • Male
  • Portal Vein/physiopathology
  • Rats
  • Rats, Inbred Lew
  • Saphenous Vein/physiopathology
  • Streptozocin
Affiliation Not a UNIGE publication
Citation (ISO format)
KAKABADZE, Zurab et al. An isolated venous sac as a novel site for cell therapy in diabetes mellitus. In: Transplantation, 2012, vol. 94, n° 4, p. 319–324. doi: 10.1097/TP.0b013e31825e4a83
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0041-1337
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