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Ophthalmic Insert versus Eye Drops for Mydriasis in Neonates: A Randomized Clinical Trial

Bremond-Gignac, Dominique
Jacqz-Aigrain, Evelyne
Abdoul, Hendy
Daruich, Alejandra
Beresniak, Ariel
Alberti, Corinne
Published in Neonatology. 2019, vol. 115, no. 2, p. 142-148
Abstract Eye drop treatment routinely used to obtain mydriasis prior to fundoscopy in neonates requires repeated instillations of mydriatic agents that can lead to systemic side effects. The aim of this study was to compare the mydriatic efficacy and tolerance of administration of phenylephrine and tropicamide via the ophthalmic insert Mydriasert® versus standard eye drop treatment in neonates.
Keywords Blood Pressure/drug effectsFemaleHeart Rate/drug effectsHumansInfantInfant, NewbornMaleMydriatics/administration & dosageOphthalmic Solutions/administration & dosagePhenylephrine/administration & dosageProspective StudiesPupil/drug effectsSingle-Blind MethodTropicamide/administration & dosageMydriasisNeonatesRetinopathy of prematurity
PMID: 30481790
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Other version: https://www.karger.com/Article/Abstract/493723
Research group Prévention des complications néonatales d'origine périnatale (990)
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BREMOND-GIGNAC, Dominique et al. Ophthalmic Insert versus Eye Drops for Mydriasis in Neonates: A Randomized Clinical Trial. In: Neonatology, 2019, vol. 115, n° 2, p. 142-148. doi: 10.1159/000493723 https://archive-ouverte.unige.ch/unige:137698

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Deposited on : 2020-06-24

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