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Scientific article
Open access
English

Phenotypes determined by cluster analysis and their survival in the prospective european scleroderma trials and research cohort of patients with systemic sclerosis

CollaboratorsChizzolini, Carlo
Published inArthritis and Rheumatology, vol. 71, no. 9, p. 1553-1570
Publication date2019
Abstract

Systemic sclerosis (SSc) is a heterogeneous connective tissue disease that is typically subdivided into limited cutaneous SSc (lcSSc) and diffuse cutaneous SSc (dcSSc) depending on the extent of skin involvement. This subclassification may not capture the entire variability of clinical phenotypes. The European Scleroderma Trials and Research (EUSTAR) database includes data on a prospective cohort of SSc patients from 122 European referral centers. This study was undertaken to perform a cluster analysis of EUSTAR data to distinguish and characterize homogeneous phenotypes without any a priori assumptions, and to examine survival among the clusters obtained.

Affiliation Not a UNIGE publication
Citation (ISO format)
SOBANSKI, Vincent et al. Phenotypes determined by cluster analysis and their survival in the prospective european scleroderma trials and research cohort of patients with systemic sclerosis. In: Arthritis and Rheumatology, 2019, vol. 71, n° 9, p. 1553–1570. doi: 10.1002/art.40906
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Article (Published version)
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ISSN of the journal2326-5191
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Technical informations

Creation11/06/2019 9:48:00 AM
First validation11/06/2019 9:48:00 AM
Update time03/15/2023 10:09:02 PM
Status update03/15/2023 10:09:00 PM
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