Experimental Abdominal Sepsis: Sticking to an Awkward but Still Useful Translational Model

Murando, Federica; Peloso, Andréa; Cobianchi, Lorenzo

doi:10.1155/2019/8971036

Scientific article

Review

English

Experimental Abdominal Sepsis: Sticking to an Awkward but Still Useful Translational Model

ContributorsMurando, Federica; Peloso, Andréa

; Cobianchi, Lorenzo

Published inMediators of Inflammation, vol. 2019, 8971036

Publication date2019

Abstract

Animal models are widely used to replicate human intra-abdominal infections. Different methodologies have been described and proposed in the scientific literature, including injection and surgical models. The aim of this review is to recapitulate the advantages and disadvantages of each method to help choose the most appropriate model for individual experimental purposes.

Keywords

Animals
Disease Models
Animal
Humans
Lipopolysaccharides / toxicity
Peritonitis / pathology
Sepsis

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de chirurgie

Research groups

Transplantation et hépatologie (905)

Citation (ISO format)

MURANDO, Federica, PELOSO, Andréa, COBIANCHI, Lorenzo. Experimental Abdominal Sepsis: Sticking to an Awkward but Still Useful Translational Model. In: Mediators of Inflammation, 2019, vol. 2019, p. 8971036. doi: 10.1155/2019/8971036

Article (Published version)

CC BY

Identifiers

PID : unige:137050
DOI : 10.1155/2019/8971036
PMID : 31885502

Additional URL for this publicationhttps://www.hindawi.com/journals/mi/2019/8971036/

Journal ISSN0962-9351

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168downloads

Creation08/01/2020 11:39:00

First validation08/01/2020 11:39:00

Update15/03/2023 22:06:02

Status update15/03/2023 22:06:02

Last indexation31/10/2024 18:54:06

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Experimental Abdominal Sepsis: Sticking to an Awkward but Still Useful Translational Model

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