Predictors of disease worsening defined by progression of organ damage in diffuse systemic sclerosis: a European Scleroderma Trials and Research (EUSTAR) analysis

Becker, Mike; Graf, Nicole; Sauter, Rafael; Allanore, Yannick; Curram, John; Denton, Christopher P; Khanna, Dinesh; Matucci-Cerinic, Marco; de Oliveira Pena, Janethe; Pope, Janet E; Distler, Oliver; EUSTAR

doi:10.1136/annrheumdis-2019-215145

Scientific article

English

Predictors of disease worsening defined by progression of organ damage in diffuse systemic sclerosis: a European Scleroderma Trials and Research (EUSTAR) analysis

ContributorsBecker, Mike; Graf, Nicole; Sauter, Rafael; Allanore, Yannick; Curram, John; Denton, Christopher P; Khanna, Dinesh; Matucci-Cerinic, Marco; de Oliveira Pena, Janethe; Pope, Janet E; Distler, Oliver; EUSTAR

CollaboratorsChizzolini, Carlo; Allai, Daniela

Published inAnnals of the Rheumatic Diseases, vol. 78, no. 9, p. 1242-1248

Publication date2019

Abstract

Mortality and worsening of organ function are desirable endpoints for clinical trials in systemic sclerosis (SSc). The aim of this study was to identify factors that allow enrichment of patients with these endpoints, in a population of patients from the European Scleroderma Trials and Research group database.

Keywords

Disease worsening
Mortality
Predictive factors
Systemic sclerosis

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Citation (ISO format)

BECKER, Mike et al. Predictors of disease worsening defined by progression of organ damage in diffuse systemic sclerosis: a European Scleroderma Trials and Research (EUSTAR) analysis. In: Annals of the Rheumatic Diseases, 2019, vol. 78, n° 9, p. 1242–1248. doi: 10.1136/annrheumdis-2019-215145