Extrastriatal 123I-FP-CIT SPECT impairment in Parkinson's disease - the PPMI cohort

Nicastro, Nicolas; Garibotto, Valentina; Burkhard, Pierre

doi:10.1186/s12883-020-01777-2

Scientific article

Open access

English

Extrastriatal 123I-FP-CIT SPECT impairment in Parkinson's disease - the PPMI cohort

ContributorsNicastro, Nicolas; Garibotto, Valentina

; Burkhard, Pierre

Published inBMC Neurology, vol. 20, no. 1, 192

Publication date2020

Abstract

Neuropathological data and nuclear medicine imaging show extensive serotonergic impairment in Parkinson's disease (PD). We undertook a case-controlled analysis of 123I-FP-CIT SPECT images to measure extrastriatal serotonergic transporters (SERT) in PD using the Parkinson's Progression Markers Initiative (PPMI) cohort.

Keywords

Dopamine
Parkinson's disease
SPECT
Serotonin

Affiliation

Research group

Citation (ISO format)

NICASTRO, Nicolas, GARIBOTTO, Valentina, BURKHARD, Pierre. Extrastriatal 123I-FP-CIT SPECT impairment in Parkinson’s disease - the PPMI cohort. In: BMC Neurology, 2020, vol. 20, n° 1, p. 192. doi: 10.1186/s12883-020-01777-2

Article (Published version)

CC BY

Identifiers

PID : unige:136726
DOI : 10.1186/s12883-020-01777-2
PMID : 32416724

Commercial URLhttps://bmcneurol.biomedcentral.com/articles/10.1186/s12883-020-01777-2

ISSN of the journal1471-2377

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Creation18/05/2020 12:47:00

First validation18/05/2020 12:47:00

Update time15/03/2023 22:03:38

Status update15/03/2023 22:03:37

Last indexation05/05/2024 16:51:11

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Extrastriatal 123I-FP-CIT SPECT impairment in Parkinson's disease - the PPMI cohort

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