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Diagnosis and treatment of pediatric pulmonary arterial hypertension

Published in Expert review of cardiovascular therapy. 2019, vol. 17, no. 3, p. 161-175
Abstract Pediatric pulmonary arterial hypertension (PAH) remains a rare and severe disease with a poor prognosis. PAH may be idiopathic, heritable or associated with systemic conditions in particular associated with congenital heart disease. Areas covered: A thorough and extensive diagnostic approach is required for a correct diagnosis. The outcome has improved over the last decade with a better diagnostic approach and with the initiation of new targeted therapies. However, there is still significant progress to achieve as there is still no cure for this devastating disease. Expert opinion: Adapted clinical studies to define the best therapeutic approach are needed. Even if the treatment approach is still mainly derived from adult data and expert consensus, several studies and registries are currently underway and should deliver important information in the next future. This review aims to give an overview of the current diagnosis and treatment strategies of PAH.
Keywords AdultChildHeart DefectsCongenital/complicationsHumansHypertensionPulmonary/physiopathology/therapyRegistries
PMID: 30698043
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Research groups Groupe Gasche-Soccal Paola (958)
L'hypertension pulmonaire (pédiatrie) (228)
(ISO format)
FARHAT, Nesrine, LADOR, Frédéric, BEGHETTI, Maurice. Diagnosis and treatment of pediatric pulmonary arterial hypertension. In: Expert Review of Cardiovascular Therapy, 2019, vol. 17, n° 3, p. 161-175. doi: 10.1080/14779072.2019.1576523 https://archive-ouverte.unige.ch/unige:136493

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Deposited on : 2020-06-05

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