en
Scientific article
Review
English

Diagnosis and treatment of pediatric pulmonary arterial hypertension

Published inExpert Review of Cardiovascular Therapy, vol. 17, no. 3, p. 161-175
Publication date2019
Abstract

Pediatric pulmonary arterial hypertension (PAH) remains a rare and severe disease with a poor prognosis. PAH may be idiopathic, heritable or associated with systemic conditions in particular associated with congenital heart disease. Areas covered: A thorough and extensive diagnostic approach is required for a correct diagnosis. The outcome has improved over the last decade with a better diagnostic approach and with the initiation of new targeted therapies. However, there is still significant progress to achieve as there is still no cure for this devastating disease. Expert opinion: Adapted clinical studies to define the best therapeutic approach are needed. Even if the treatment approach is still mainly derived from adult data and expert consensus, several studies and registries are currently underway and should deliver important information in the next future. This review aims to give an overview of the current diagnosis and treatment strategies of PAH.

Keywords
  • Adult
  • Child
  • Heart Defects
  • Congenital/complications
  • Humans
  • Hypertension
  • Pulmonary/physiopathology/therapy
  • Registries
Citation (ISO format)
FARHAT, Nesrine, LADOR, Frédéric, BEGHETTI, Maurice. Diagnosis and treatment of pediatric pulmonary arterial hypertension. In: Expert Review of Cardiovascular Therapy, 2019, vol. 17, n° 3, p. 161–175. doi: 10.1080/14779072.2019.1576523
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Article (Published version)
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Identifiers
ISSN of the journal1477-9072
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Technical informations

Creation10/28/2019 11:12:00 AM
First validation10/28/2019 11:12:00 AM
Update time03/15/2023 10:02:25 PM
Status update03/15/2023 10:02:25 PM
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