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Resting-State Brain Activity for Early Prediction Outcome in Postanoxic Patients in a Coma with Indeterminate Clinical Prognosis

Publication date2020
Abstract

Early outcome prediction of postanoxic patients in a coma after cardiac arrest proves challenging. Current prognostication relies on multimodal testing, using clinical examination, electrophysiologic testing, biomarkers, and structural MR imaging. While this multimodal prognostication is accurate for predicting poor outcome (ie, death), it is not sensitive enough to identify good outcome (ie, consciousness recovery), thus leaving many patients with indeterminate prognosis. We specifically assessed whether resting-state fMRI provides prognostic information, notably in postanoxic patients in a coma with indeterminate prognosis early after cardiac arrest, specifically for good outcome.

Citation (ISO format)
PUGIN, Deborah et al. Resting-State Brain Activity for Early Prediction Outcome in Postanoxic Patients in a Coma with Indeterminate Clinical Prognosis. In: American Journal of Neuroradiology, 2020. doi: 10.3174/ajnr.A6572
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Article (Published version)
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ISSN of the journal0195-6108
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Creation05/27/2020 1:40:00 PM
First validation05/27/2020 1:40:00 PM
Update time03/15/2023 10:01:55 PM
Status update03/15/2023 10:01:54 PM
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