Mild hyperthermia by MR-guided focused ultrasound in an ex vivo model of osteolytic bone tumour: optimization of the spatio-temporal control of the delivered temperature

Guillemin, Pauline Coralie; Gui Levy, Laura; Lorton, Orane; Zilli, Thomas; Crowe, Lindsey; Desgranges, Stéphane; Montet, Xavier Cédric Rodolphe; Terraz, Sylvain; Miralbell, Raymond; Salomir, Rares; Boudabbous, Sana

doi:10.1186/s12967-019-2094-x

Scientific article

Open access

English

Mild hyperthermia by MR-guided focused ultrasound in an ex vivo model of osteolytic bone tumour: optimization of the spatio-temporal control of the delivered temperature

ContributorsGuillemin, Pauline Coralie

; Gui Levy, Laura; Lorton, Orane; Zilli, Thomas; Crowe, Lindsey; Desgranges, Stéphane; Montet, Xavier Cédric Rodolphe; Terraz, Sylvain; Miralbell, Raymond; Salomir, Rares; Boudabbous, Sana

Published inJournal of Translational Medicine, vol. 17, no. 1, 350

Publication date2019

Abstract

Magnetic resonance guided focused ultrasound was suggested for the induction of deep localized hyperthermia adjuvant to radiation- or chemotherapy. In this study we are aiming to validate an experimental model for the induction of uniform temperature elevation in osteolytic bone tumours, using the natural acoustic window provided by the cortical breakthrough.

Keywords

Adjuvant hyperthermia
Osteolytic tumours
MR-guided focused ultrasound
Temperature control

Affiliation

Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale

Research group

Citation (ISO format)

GUILLEMIN, Pauline Coralie et al. Mild hyperthermia by MR-guided focused ultrasound in an ex vivo model of osteolytic bone tumour: optimization of the spatio-temporal control of the delivered temperature. In: Journal of Translational Medicine, 2019, vol. 17, n° 1, p. 350. doi: 10.1186/s12967-019-2094-x