Mild hyperthermia by MR-guided focused ultrasound in an ex vivo model of osteolytic bone tumour: optimization of the spatio-temporal control of the delivered temperature

Guillemin, Pauline Coralie; Gui Levy, Laura; Lorton, Orane; Zilli, Thomas; Crowe, Lindsey; Desgranges, Stéphane; Montet, Xavier Cédric Rodolphe; Terraz, Sylvain; Miralbell, Raymond; Salomir, Rares; Boudabbous, Sana

doi:10.1186/s12967-019-2094-x

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Title		Mild hyperthermia by MR-guided focused ultrasound in an ex vivo model of osteolytic bone tumour: optimization of the spatio-temporal control of the delivered temperature
Authors		Guillemin, Pauline Coralie Gui Levy, Laura Lorton, Orane Zilli, Thomas Crowe, Lindsey Desgranges, Stéphane Montet, Xavier Cédric Rodolphe Terraz, Sylvain Miralbell, Raymond Salomir, Rares Boudabbous, Sana show all authors [1 - 11]
Published in		Journal of Translational Medicine. 2019, vol. 17, no. 1, 350
Abstract		Magnetic resonance guided focused ultrasound was suggested for the induction of deep localized hyperthermia adjuvant to radiation- or chemotherapy. In this study we are aiming to validate an experimental model for the induction of uniform temperature elevation in osteolytic bone tumours, using the natural acoustic window provided by the cortical breakthrough.
Keywords		Adjuvant hyperthermia — Osteolytic tumours — MR-guided focused ultrasound — Temperature control
Identifiers		DOI: 10.1186/s12967-019-2094-x PMID: 31651311
Full text		Article (Published version) (3.2 MB) - Free access Other version: https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-019-2094-x
Structures		Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research groups		Laboratoire de radiothérapie de haute précision pour le cancer de la prostate (1014) Imagerie per-opératoire multi-modalité en radiologie interventionnelle (949)
Citation (ISO format)		GUILLEMIN, Pauline Coralie et al. Mild hyperthermia by MR-guided focused ultrasound in an ex vivo model of osteolytic bone tumour: optimization of the spatio-temporal control of the delivered temperature. In: Journal of Translational Medicine, 2019, vol. 17, n° 1, p. 350. doi: 10.1186/s12967-019-2094-x https://archive-ouverte.unige.ch/unige:136218