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Oligometastatic prostate cancer: The game is afoot

Dirix, Piet
Everaerts, Wouter
Gomez-Iturriaga, Alfonso
Ingrosso, Gianluca
Liefhooghe, Nick
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Published in Cancer treatment reviews. 2019, vol. 73, p. 84-90
Abstract Oligometastatic prostate cancer represents an intermediate state between a localized tumor and widespread metastatic disease. Its specific clinical features suggest the existence of a distinct biology which still needs to be elucidated. New imaging techniques like prostate specific membrane antigen (PSMA) PET scans have shown to perform well in the staging and restaging of this category of patients, at different phases of disease evolution. Despite limited prospective evidence, metastasis-directed therapies (MDT) are emerging as valid treatment options able to postpone systemic therapies and probably improve survival outcome. The aim of this review is to shed light on the clinical scenario of prostate cancer patients with limited metastatic disease burden and highlight the role of MDT strategies in this setting.
Keywords Prostate cancerOligometastaticRadiotherapyDe novoOligorecurrentOligoprogressive
PMID: 30684842
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Research group Laboratoire de radiothérapie de haute précision pour le cancer de la prostate (1014)
Autre: Swiss Prostate Cancer Award from the Movember Foundation
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LANCIA, Andréa et al. Oligometastatic prostate cancer: The game is afoot. In: Cancer Treatment Reviews, 2019, vol. 73, p. 84-90. doi: 10.1016/j.ctrv.2019.01.005 https://archive-ouverte.unige.ch/unige:136216

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Deposited on : 2020-05-26

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