Impact of mitral regurgitation on clinical outcomes of patients with low-ejection fraction, low-gradient severe aortic stenosis undergoing transcatheter aortic valve implantation

O'Sullivan, Crochan J; Stortecky, Stefan; Bütikofer, Anne; Heg, Dik; Zanchin, Thomas; Huber, Christoph; Pilgrim, Thomas; Praz, Fabien; Buellesfeld, Lutz; Khattab, Ahmed A; Blöchlinger, Stefan; Carrel, Thierry; Meier, Bernhard; Zbinden, Stephan; Wenaweser, Peter; Windecker, Stephan

doi:10.1161/CIRCINTERVENTIONS.114.001895

Scientific article

English

Impact of mitral regurgitation on clinical outcomes of patients with low-ejection fraction, low-gradient severe aortic stenosis undergoing transcatheter aortic valve implantation

ContributorsO'Sullivan, Crochan J; Stortecky, Stefan; Bütikofer, Anne; Heg, Dik; Zanchin, Thomas; Huber, Christoph

; Pilgrim, Thomas; Praz, Fabien; Buellesfeld, Lutz; Khattab, Ahmed A; Blöchlinger, Stefan; Carrel, Thierry; Meier, Bernhard; Zbinden, Stephan; Wenaweser, Peter; Windecker, Stephan

Published inCirculation. Cardiovascular Interventions, vol. 8, no. 2, e001895

Publication date2015

Abstract

Up to 1 in 6 patients undergoing transcatheter aortic valve implantation (TAVI) present with low-ejection fraction, low-gradient (LEF-LG) severe aortic stenosis and concomitant relevant mitral regurgitation (MR) is present in 30% to 55% of these patients. The effect of MR on clinical outcomes of LEF-LG patients undergoing TAVI is unknown.

Keywords

Aged
Aged, 80 and over
Aortic Valve Stenosis/complications/diagnosis/mortality/physiopathology/therapy
Cardiac Catheterization/adverse effects/methods/mortality
Female
Heart Valve Prosthesis Implantation/adverse effects/methods/mortality
Humans
Kaplan-Meier Estimate
Male
Mitral Valve Insufficiency/complications/diagnosis/mortality/physiopathology/therapy
Patient Selection
Proportional Hazards Models
Risk Assessment
Risk Factors
Stroke Volume
Switzerland
Time Factors
Treatment Outcome
Ventricular Function, Left

Affiliation entities

Not a UNIGE publication

Citation (ISO format)

O’SULLIVAN, Crochan J et al. Impact of mitral regurgitation on clinical outcomes of patients with low-ejection fraction, low-gradient severe aortic stenosis undergoing transcatheter aortic valve implantation. In: Circulation. Cardiovascular Interventions, 2015, vol. 8, n° 2, p. e001895. doi: 10.1161/CIRCINTERVENTIONS.114.001895

Article (Published version)

Supplemental data

Identifiers

PID : unige:136138
DOI : 10.1161/CIRCINTERVENTIONS.114.001895
PMID : 25657315

Additional URL for this publicationhttps://www.ahajournals.org/doi/10.1161/CIRCINTERVENTIONS.114.001895

Journal ISSN1941-7640

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Impact of mitral regurgitation on clinical outcomes of patients with low-ejection fraction, low-gradient severe aortic stenosis undergoing transcatheter aortic valve implantation

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