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Title

Viral diversity based on next-generation sequencing of HIV-1 provides precise estimates of infection recency and time since infection

Authors
Carlisle, Louisa A
Turk, Teja
Kusejko, Katharina
Metzner, Karin J
Leemann, Christine
Schenkel, Corinne D
Bachmann, Nadine
Posada, Susana
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Published in The Journal of Infectious Diseases. 2019, vol. 220, no. 2, p. 254-265
Abstract Human immunodeficiency virus type 1 (HIV-1) genetic diversity increases over the course of infection and can be used to infer the time since infection and, consequently, infection recency, which are crucial for HIV-1 surveillance and the understanding of viral pathogenesis.
Keywords HIV-1DiversityInfection recencyNext-generation sequencingTime since infection
Identifiers
PMID: 30835266
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Article (Published version) (3.1 MB) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research groups Groupe Laurent Kaiser (virologie clinique) (668)
VIH/SIDA (930)
Projects FNS: BSSGI0_155851
FNS: 177499
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(ISO format)
CARLISLE, Louisa A et al. Viral diversity based on next-generation sequencing of HIV-1 provides precise estimates of infection recency and time since infection. In: The Journal of Infectious Diseases, 2019, vol. 220, n° 2, p. 254-265. doi: 10.1093/infdis/jiz094 https://archive-ouverte.unige.ch/unige:136095

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Deposited on : 2020-05-25

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