Scientific article
English

A spatio-temporal model for spontaneous thrombus formation in cerebral aneurysms

Published inJournal of Theoretical Biology, vol. 394, p. 68-76
Publication date2016
Abstract

We propose a new numerical model to describe thrombus formation in cerebral aneurysms. This model combines CFD simulations with a set of bio-mechanical processes identified as being the most important to describe the phenomena at a large space and time scales. The hypotheses of the model are based on in vitro experiments and clinical observations. We document that we can reproduce very well the shape and volume of patient specific thrombus segmented in giant aneurysms.

Keywords
  • Blood-flow
  • Lattice Boltzmann
  • Cerebral aneurysm
  • Clotting
  • Thrombosis
  • Numerical modelling
Citation (ISO format)
MALASPINAS, Orestis Pileas et al. A spatio-temporal model for spontaneous thrombus formation in cerebral aneurysms. In: Journal of Theoretical Biology, 2016, vol. 394, p. 68–76. doi: 10.1016/j.jtbi.2015.12.022
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Article (Published version)
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Identifiers
Journal ISSN0022-5193
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