en
Scientific article
Review
English

Emerging biomarkers for cardiac arrhythmias

Published inClinical Biochemistry, vol. 75, p. 1-6
Publication date2020
Abstract

Cardiac arrhythmias are associated with substantial morbidity and mortality. Recent advances in the pathophysiological understanding of cardiac arrhythmia indicate that inflammation, fibrosis, and even autoimmune mechanisms could facilitate the development of arrhythmias by interfering either with fibroblast activation-related electrical remodeling or with the function of different cardiac ion channels, leading to the emerging concepts of autoimmune and inflammatory channelopathies. In this descriptive review, we considered recent data of the literature focusing on biomarkers reflecting the degree of inflammation, myocardial stretch, fibrosis and sustained B-cell activation as potential additional diagnostic, risk stratification tools and potential therapeutic targets in cardiac arrhythmia.

Keywords
  • Biomarkers
  • Cardiac arrhythmias
  • Inflammation
  • Fibrosis
  • Autoimmunity
Citation (ISO format)
HAMMERER-LERCHER, Angelika, NAMDAR, Mehdi, VUILLEUMIER, Nicolas. Emerging biomarkers for cardiac arrhythmias. In: Clinical Biochemistry, 2020, vol. 75, p. 1–6. doi: 10.1016/j.clinbiochem.2019.11.012
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Article (Published version)
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Identifiers
ISSN of the journal0009-9120
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Technical informations

Creation05/11/2020 2:23:00 PM
First validation05/11/2020 2:23:00 PM
Update time03/15/2023 9:55:46 PM
Status update03/15/2023 9:55:45 PM
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