Peak Width of Skeletonized Mean Diffusivity as a Marker of Diffuse Cerebrovascular Damage

Low, Audrey; Mak, Elijah; Stefaniak, James D.; Malpetti, Maura; Nicastro, Nicolas; Savulich, George; Chouliaras, Leonidas; Markus, Hugh S.; Rowe, James B.; O'Brien, John T.

doi:10.3389/fnins.2020.00238

Scientific article

Open access

English

Peak Width of Skeletonized Mean Diffusivity as a Marker of Diffuse Cerebrovascular Damage

ContributorsLow, Audrey; Mak, Elijah; Stefaniak, James D.; Malpetti, Maura; Nicastro, Nicolas; Savulich, George; Chouliaras, Leonidas; Markus, Hugh S.; Rowe, James B.; O'Brien, John T.

Published inFrontiers in Neuroscience, vol. 14, no. 238

Publication date2020

Abstract

The peak width of skeletonized mean diffusivity (PSMD) has been proposed as a fully automated imaging marker of relevance to cerebral small vessel disease (SVD). We assessed PSMD in relation to conventional SVD markers, global measures of neurodegeneration, and cognition.

Keywords

Small vessel disease
Magnetic resonance imaging
Diffusion tensor imaging
White matter
Hyperintensities
Cognition
Dementia

Affiliation

Faculté de médecine / Section de médecine clinique / Département des neurosciences cliniques

Citation (ISO format)

LOW, Audrey et al. Peak Width of Skeletonized Mean Diffusivity as a Marker of Diffuse Cerebrovascular Damage. In: Frontiers in Neuroscience, 2020, vol. 14, n° 238. doi: 10.3389/fnins.2020.00238

Article (Published version)

CC BY

Identifiers

PID : unige:134859
DOI : 10.3389/fnins.2020.00238
PMID : 32265640

Commercial URLhttps://www.frontiersin.org/article/10.3389/fnins.2020.00238/full

ISSN of the journal1662-453X

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Creation03/19/2020 5:28:00 PM

First validation03/19/2020 5:28:00 PM

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Peak Width of Skeletonized Mean Diffusivity as a Marker of Diffuse Cerebrovascular Damage

The peak width of skeletonized mean diffusivity (PSMD) has been proposed as a fully automated imaging marker of relevance to cerebral small vessel disease (SVD). We assessed PSMD in relation to conventional SVD markers, global measures of neurodegeneration, and cognition.

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