Scientific article
Open access

Application of 3D printed tools for customized open port probe-electrospray mass spectrometry

Published inTalanta, vol. 215, 120894
Publication date2020

Three dimensional printed open port probe (3DP-OPP) and air displacement based liquid handler, were designed and optimized using fused deposition modeling (FDM) and stereolitography (SLA) 3D printing. The performance of the devices were investigated for the analysis of solid and liquid samples with electrospray ionization mass spectrometry (ESI-MS). Direct analysis in less than 1 min and without any sample preparation, enabled detection of pesticides (azoxtystrobin/imazalil) on fruits peel surface and illegal substances (MDMA/MDEA) in home-made pills. Conjunction of OPP in the overspill mode with a customized autosampler, equipped with disposable pipette tips, enables direct quantitative analysis of drugs of abuse in urine and plasma, with minimized carry-over and reduced matrix effect compared to flow injection analysis.

  • Open port probe
  • Mass spectrometry
  • Electrospray
  • Direct analysis
  • 3D printing
  • Fused deposition modeling
  • Stereolithography
Citation (ISO format)
SOSNOWSKI, Piotr, HOPFGARTNER, Gerard. Application of 3D printed tools for customized open port probe-electrospray mass spectrometry. In: Talanta, 2020, vol. 215, p. 120894. doi: 10.1016/j.talanta.2020.120894
Main files (1)
Article (Published version)
ISSN of the journal0165-2486

Technical informations

Creation04/14/2020 1:45:00 PM
First validation04/14/2020 1:45:00 PM
Update time03/15/2023 9:31:30 PM
Status update03/15/2023 9:31:30 PM
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