Effect of PEEP and I:E ratio on cerebral oxygenation in ARDS: an experimental study in anesthetized rabbit

Lovisari, Federica; Fodor, Gergely; Petak, Ferenc; Habre, Walid; Bayat, Sam

doi:10.1186/s12871-019-0782-y

Scientific article

English

Effect of PEEP and I:E ratio on cerebral oxygenation in ARDS: an experimental study in anesthetized rabbit

ContributorsLovisari, Federica; Fodor, Gergely; Petak, Ferenc; Habre, Walid; Bayat, Sam

Published inBMC Anesthesiology, vol. 19, no. 1, 110

Publication date2019

Abstract

Although PEEP and inversed I:E ratio have been shown to improve gas exchange in ARDS, both can adversely affect systemic hemodynamics and cerebral perfusion. The goal of this study was to assess how changes in PEEP and I:E ratio affect systemic and cerebral oxygenation and perfusion in normal and injured lung.

Keywords

Mechanical ventilation
Near-infrared spectrometry
Blood flow/regional
Acute respiratory distress
Syndrome
Lung function
Hemodynamics

Affiliation entities

Research groups

Funding

Swiss National Science Foundation - Experimental and clinical assessments of the benefit of variable ventilation in diseased lungs [169334]

Citation (ISO format)

LOVISARI, Federica et al. Effect of PEEP and I:E ratio on cerebral oxygenation in ARDS: an experimental study in anesthetized rabbit. In: BMC Anesthesiology, 2019, vol. 19, n° 1, p. 110. doi: 10.1186/s12871-019-0782-y

Article (Published version)

CC BY

Supplemental data

CC BY

Identifiers

PID : unige:134709
DOI : 10.1186/s12871-019-0782-y
PMID : 31216981

Journal ISSN1471-2253

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Creation05/11/2019 21:58:00

First validation05/11/2019 21:58:00

Update17/01/2025 16:51:03

Status update17/01/2025 16:51:03

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Effect of PEEP and I:E ratio on cerebral oxygenation in ARDS: an experimental study in anesthetized rabbit

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