UNIGE document Scientific Article
previous document  unige:134616  next document
add to browser collection
Title

Perioperative chemotherapy for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial

Authors
Al-Batran, Salah-Eddin
Homann, Nils
Pauligk, Claudia
Goetze, Thorsten O
Meiler, Johannes
Kasper, Stefan
Kopp, Hans-Georg
Mayer, Frank
show hidden authors show all authors [1 - 57]
Collaboration
Published in The Lancet. 2019, vol. 393, no. 10184, p. 1948-1957
Abstract Docetaxel-based chemotherapy is effective in metastatic gastric and gastro-oesophageal junction adenocarcinoma. This study reports on the safety and efficacy of the docetaxel-based triplet FLOT (fluorouracil plus leucovorin, oxaliplatin and docetaxel) as a perioperative therapy for patients with locally advanced, resectable tumours.
Keywords Adenocarcinoma/drug therapy/pathologyAdministration, OralAdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy Protocols/administration & dosage/therapeutic useCapecitabine/administration & dosage/therapeutic useCisplatin/administration & dosage/therapeutic useDigestive System Surgical ProceduresDisease-Free SurvivalDocetaxel/administration & dosage/therapeutic useEsophagogastric Junction/pathologyFemaleFluorouracil/administration & dosage/therapeutic useHumansLeucovorin/administration & dosage/therapeutic useMaleMiddle AgedNeoplasm StagingOxaliplatin/administration & dosage/therapeutic useStomach Neoplasms/drug therapy/pathologyTreatment Outcome
Identifiers
PMID: 30982686
Full text
Article (Published version) (484 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Appendix (673 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Other version: https://www.sciencedirect.com/science/article/pii/S0140673618325571
Structures
Research group Transplantation et hépatologie (905)
Citation
(ISO format)
AL-BATRAN, Salah-Eddin et al. Perioperative chemotherapy for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial. In: The Lancet, 2019, vol. 393, n° 10184, p. 1948-1957. doi: 10.1016/S0140-6736(18)32557-1 https://archive-ouverte.unige.ch/unige:134616

138 hits

0 download

Update

Deposited on : 2020-04-15

Export document
Format :
Citation style :