Interictal epileptogenic zone localization in patients with focal epilepsy using electric source imaging and directed functional connectivity from low‐density EEG

Coito, Ana; Biethahn, Silke; Tepperberg, Janina; Carboni, Margherita; Roelcke, Ulrich; Seeck, Margitta; Mierlo, Pieter; Gschwind, Markus; Vulliemoz, Serge

doi:10.1002/epi4.12318

Scientific article

English

Interictal epileptogenic zone localization in patients with focal epilepsy using electric source imaging and directed functional connectivity from low‐density EEG

ContributorsCoito, Ana; Biethahn, Silke; Tepperberg, Janina; Carboni, Margherita; Roelcke, Ulrich; Seeck, Margitta; Mierlo, Pieter; Gschwind, Markus; Vulliemoz, Serge

Published inEpilepsia Open, vol. 4, no. 2, p. 281-292

Publication date2019

Abstract

Electrical source imaging (ESI) is used increasingly to estimate the epileptogenic zone (EZ) in patients with epilepsy. Directed functional connectivity (DFC) coupled to ESI helps to better characterize epileptic networks, but studies on interictal activity have relied on high‐density recordings. We investigated the accuracy of ESI and DFC for localizing the EZ, based on low‐density clinical electroencephalography (EEG).

Keywords

Directed functional connectivity
Electrical source imaging
Epileptogenic zone
Focal epilepsy
Low-density EEG

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département des neurosciences cliniques

Research groups

Funding

Swiss National Science Foundation - Local and global brain connectivity alterations in focal epilepsy: Effects of disease, surgery and neuromodulation [169198]
Swiss National Science Foundation - 320030-169198, 163398, and CRSII5_170873

Citation (ISO format)

COITO, Ana et al. Interictal epileptogenic zone localization in patients with focal epilepsy using electric source imaging and directed functional connectivity from low‐density EEG. In: Epilepsia Open, 2019, vol. 4, n° 2, p. 281–292. doi: 10.1002/epi4.12318