en
Scientific article
Review
English

Fracture risk following intermission of osteoporosis therapy

Published inOsteoporosis International, vol. 30, no. 9, p. 1733-1743
Publication date2019
Abstract

Given the widespread practice of recommending drug holidays, we reviewed the impact of medication discontinuation of two common anti-osteoporosis therapies (bisphosphonates and denosumab). Trial evidence suggests the risk of new clinical fractures, and vertebral fracture increases when osteoporosis treatment with bisphosphonates or denosumab is stopped.

Keywords
  • Atypical fracture
  • Bisphosphonates
  • Denosumab
  • Drug holiday.
Citation (ISO format)
DENNISON, E.M. et al. Fracture risk following intermission of osteoporosis therapy. In: Osteoporosis International, 2019, vol. 30, n° 9, p. 1733–1743. doi: 10.1007/s00198-019-05002-w
Main files (1)
Article (Published version)
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Identifiers
ISSN of the journal0937-941X
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Creation12/12/2019 1:42:00 PM
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