Privat-docent thesis
Open access

Multidimensional restitution of the vestibular function with a vestibular implant

ContributorsGuinand, Nils
Defense date2019

Bilateral loss of the vestibular (BV) function leads to chronic imbalance and oscillopsia. This condition has a significant negative impact on quality of life, indicating a need to remedy the lack of effective treatment. The concept of the vestibular implant (VI) has emerged, it consists of a modified cochlear implant stimulator with one up to three additional electrodes positioned in contact with the vestibular nerve. An external processor, fed with motion information captured by a head-fixed motion sensor, is connected to the implanted stimulator. Finally motion modulated electrical stimulation is delivered to the vestibular nerve. Up to now, 13 patients with a BV loss have been implanted. We demonstrated that it is possible to significantly improve or in certain cases to normalize the vestibulo-ocular reflex (VOR) gains. We further showed that the vestibulo-collic reflex could be elicited and that controlled postural responses could be obtained. Finally, the dynamic visual acuity (DVA) while walking has been significantly improved, or even normalized, in 6 subjects. This was the first demonstration of a functional rehabilitation. The presented results reflect the potential of the VI towards a clinically useful device. Moreover, by providing selective stimulations of the vestibular system, the VI opens doors to push the vestibular research beyond the traditional boundaries.

  • Vestibular Implant
  • Bilateral vestibulopathy
Citation (ISO format)
GUINAND, Nils. Multidimensional restitution of the vestibular function with a vestibular implant. 2019. doi: 10.13097/archive-ouverte/unige:134022
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Creation04/02/2020 5:51:00 PM
First validation04/02/2020 5:51:00 PM
Update time03/15/2023 9:26:59 PM
Status update03/15/2023 9:26:59 PM
Last indexation01/29/2024 10:10:11 PM
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