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Title

Electromembrane extraction: Overview of the last decade

Authors
Kubáň, Pavel
Pedersen-Bjergaard, Stig
Published in TrAC Trends in Analytical Chemistry. 2019, vol. 113, p. 357-363
Abstract Ticagrelor is a highly recommended new antiplatelet agent for the treatment of patients with acute coronary syndrome at moderate or high ischemic risk. There is a real need for rapid and accurate analytical methods for ticagrelor determination in biological fluids for pharmacokinetic studies. In this study, a sensitive and specific LC-MS method was developed and validated for quantification of ticagrelor and its active metabolite (AM) in human plasma over expected clinical concentrations.
Keywords Biological matrixLC-MS/MSQuantificationTicagrelor.
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Structures
Research group Sciences analytiques
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DROUIN, Nicolas et al. Electromembrane extraction: Overview of the last decade. In: TrAC Trends in Analytical Chemistry, 2019, vol. 113, p. 357-363. doi: 10.1016/j.trac.2018.10.024 https://archive-ouverte.unige.ch/unige:133095

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Deposited on : 2020-03-25

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