Personalized Ertapenem Prophylaxis for Carriers of Extended-spectrum β-Lactamase-producing Enterobacteriaceae Undergoing Colorectal Surgery

Nutman, Amir; Temkin, Elizabeth; Harbarth, Stéphan Juergen; Carevic, Biljana; Ris, Frédéric; Fankhauser-Rodriguez, Carolina; Radovanovic, Ivana; Dubinsky-Pertzov, Biana; Cohen-Percia, Shimrit; Kariv, Yehuda; Buchs, Nicolas; Schiffer, Eduardo; Fallach, Noga; Klausner, Joseph; Carmeli, Yehuda; Resistance in Gram-negative Organisms: Studying Intervention Strategies (R-GNOSIS) WP4 Study Group

doi:10.1093/cid/ciz524

Scientific article

English

Personalized Ertapenem Prophylaxis for Carriers of Extended-spectrum β-Lactamase-producing Enterobacteriaceae Undergoing Colorectal Surgery

ContributorsNutman, Amir; Temkin, Elizabeth; Harbarth, Stéphan Juergen

; Carevic, Biljana; Ris, Frédéric; Fankhauser-Rodriguez, Carolina; Radovanovic, Ivana; Dubinsky-Pertzov, Biana; Cohen-Percia, Shimrit; Kariv, Yehuda; Buchs, Nicolas; Schiffer, Eduardo; Fallach, Noga; Klausner, Joseph; Carmeli, Yehuda; Resistance in Gram-negative Organisms: Studying Intervention Strategies (R-GNOSIS) WP4 Study Group

Published inClinical Infectious Diseases

Publication date2019

Abstract

Carriers of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) who receive cephalosporin-based prophylaxis have twice the risk of surgical site infection (SSI) following colorectal surgery as noncarriers. We tested whether ESBL-PE screening and personalized prophylaxis with ertapenem reduces SSI risk among carriers.

Keywords

Antibiotic prophylaxis
Colorectal surgery
Ertapenem
Extended-spectrum β-lactamase
Surgical site infection

Affiliation

Research group

Epidémiologie et contrôle de la résistance aux antibiotiques (866)

Citation (ISO format)

NUTMAN, Amir et al. Personalized Ertapenem Prophylaxis for Carriers of Extended-spectrum β-Lactamase-producing Enterobacteriaceae Undergoing Colorectal Surgery. In: Clinical Infectious Diseases, 2019. doi: 10.1093/cid/ciz524

Article (Published version)

Identifiers

PID : unige:132725
DOI : 10.1093/cid/ciz524
PMID : 31613316

ISSN of the journal1058-4838

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Creation10/30/2019 3:25:00 PM

First validation10/30/2019 3:25:00 PM

Update time03/15/2023 9:18:10 PM

Status update03/15/2023 9:18:07 PM

Last indexation01/17/2024 9:15:15 AM

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Personalized Ertapenem Prophylaxis for Carriers of Extended-spectrum β-Lactamase-producing Enterobacteriaceae Undergoing Colorectal Surgery

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