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Personalized Ertapenem Prophylaxis for Carriers of Extended-spectrum β-Lactamase-producing Enterobacteriaceae Undergoing Colorectal Surgery

ContributorsNutman, Amir; Temkin, Elizabeth; Harbarth, Stéphan Juergenorcid; Carevic, Biljana; Ris, Frédéric; Fankhauser-Rodriguez, Carolina; Radovanovic, Ivana; Dubinsky-Pertzov, Biana; Cohen-Percia, Shimrit; Kariv, Yehuda; Buchs, Nicolas; Schiffer, Eduardo; Fallach, Noga; Klausner, Joseph; Carmeli, Yehuda; Resistance in Gram-negative Organisms: Studying Intervention Strategies (R-GNOSIS) WP4 Study Group
Published inClinical Infectious Diseases
Publication date2019
Abstract

Carriers of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) who receive cephalosporin-based prophylaxis have twice the risk of surgical site infection (SSI) following colorectal surgery as noncarriers. We tested whether ESBL-PE screening and personalized prophylaxis with ertapenem reduces SSI risk among carriers.

Keywords
  • Antibiotic prophylaxis
  • Colorectal surgery
  • Ertapenem
  • Extended-spectrum β-lactamase
  • Surgical site infection
Affiliation
Research group
Citation (ISO format)
NUTMAN, Amir et al. Personalized Ertapenem Prophylaxis for Carriers of Extended-spectrum β-Lactamase-producing Enterobacteriaceae Undergoing Colorectal Surgery. In: Clinical Infectious Diseases, 2019. doi: 10.1093/cid/ciz524
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Article (Published version)
accessLevelRestricted
Secondary files (1)
Identifiers
ISSN of the journal1058-4838
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Technical informations

Creation10/30/2019 3:25:00 PM
First validation10/30/2019 3:25:00 PM
Update time03/15/2023 9:18:10 PM
Status update03/15/2023 9:18:07 PM
Last indexation05/05/2024 4:35:30 PM
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