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Title

Amyloid Load, Hippocampal Volume Loss, and Diffusion Tensor Imaging Changes in Early Phases of Brain Aging

Authors
Lilja, Johan
Published in Frontiers in Neuroscience. 2019, vol. 13, p. 1228
Abstract Amyloid imaging, gray matter (GM) morphometry and diffusion tensor imaging (DTI) have all been used as predictive biomarkers in dementia. Our objective was to define the imaging profile of healthy elderly controls as a function of their cognitive trajectories and explore whether amyloid burden and white matter (WM) microstructure changes are associated with subtle decrement of neuropsychological performances in old age.
Keywords Amyloid depositionAPOE genotypingMagnetic resonance imagingNormal agingPositron emissionTomography
Identifiers
PMID: 31803008
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Research groups Démence du sujet âgé, troubles cognitifs, la symptomatologie cognitive (577)
Groupe Giannakopoulos Panteleimon (psychiatrie générale) (201)
Laboratoire de neuroimagerie et de traceurs moléculaires innovants (984)
Imagerie per-opératoire multi-modalité en radiologie interventionnelle (949)
Project FNS: 320030-169390
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(ISO format)
HALLER, Sven et al. Amyloid Load, Hippocampal Volume Loss, and Diffusion Tensor Imaging Changes in Early Phases of Brain Aging. In: Frontiers in Neuroscience, 2019, vol. 13, p. 1228. doi: 10.3389/fnins.2019.01228 https://archive-ouverte.unige.ch/unige:132448

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Deposited on : 2020-03-18

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