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Title

Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort

Authors
Kim, Min
Snowden, Stuart
Suvitaival, Tommi
Ali, Ashfaq
Merkler, David J
Ahmad, Tahmina
Westwood, Sarah
Baird, Alison
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Published in Alzheimer's & Dementia. 2019, vol. 15, no. 6, p. 817-827
Abstract A critical and as-yet unmet need in Alzheimer's disease (AD) is the discovery of peripheral small molecule biomarkers. Given that brain pathology precedes clinical symptom onset, we set out to test whether metabolites in blood associated with pathology as indexed by cerebrospinal fluid (CSF) AD biomarkers.
Keywords EMIF-ADAlzheimer’s diseaseDementiaAmyloidTauCSFBrain volume measurementsCognitive function measurementsMetabolomicsBiomarkers
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PMID: 31078433
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Research group Troubles de mémoire et maladie d'Alzeimer (935)
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KIM, Min et al. Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort. In: Alzheimer's & Dementia, 2019, vol. 15, n° 6, p. 817-827. doi: 10.1016/j.jalz.2019.03.004 https://archive-ouverte.unige.ch/unige:132383

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Deposited on : 2020-03-17

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