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Scientific article
English

Genetic polymorphisms associated with smoking behaviour predict the risk of surgery in patients with Crohn's disease

Published inAlimentary Pharmacology & Therapeutics, vol. 47, no. 1, p. 55-66
Publication date2018
Abstract

Smoking is a strong environmental factor leading to adverse outcomes in Crohn's disease, but a more benign course in ulcerative colitis. Several single nucleotide polymorphisms (SNPs) are associated with smoking quantity and behaviour.

Keywords
  • Adult
  • Alleles
  • Cohort Studies
  • Colitis
  • Ulcerative/genetics/surgery
  • Crohn Disease/genetics/surgery
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Polymorphism
  • Single Nucleotide
  • Proctitis/epidemiology
  • Prospective Studies
  • Risk Factors
  • Smoking/adverse effects/epidemiology
  • Young Adult
Funding
  • Swiss National Science Foundation - 32473B‐156525, 3347CO‐108792
  • Autre - Swiss Cancer League. Grant Number: KFS‐2977‐08‐2012
Citation (ISO format)
LANG, B M et al. Genetic polymorphisms associated with smoking behaviour predict the risk of surgery in patients with Crohn’s disease. In: Alimentary Pharmacology & Therapeutics, 2018, vol. 47, n° 1, p. 55–66. doi: 10.1111/apt.14378
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Article (Published version)
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Identifiers
ISSN of the journal0269-2813
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