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Nutrient Intake in the First Two Weeks of Life and Brain Growth in Preterm Neonates

Schneider, Juliane
Fischer Fumeaux, Céline J
Duerden, Emma G
Guo, Ting
Foong, Justin
Graz, Myriam Bickle
Hagmann, Patric
Chakravarty, M Mallar
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Published in Pediatrics. 2018, vol. 141, no. 3, e20172169
Abstract Optimizing early nutritional intake in preterm neonates may promote brain health and neurodevelopment through enhanced brain maturation. Our objectives were (1) to determine the association of energy and macronutrient intake in the first 2 weeks of life with regional and total brain growth and white matter (WM) maturation, assessed by 3 serial MRI scans in preterm neonates; (2) to examine how critical illness modifies this association; and (3) to investigate the relationship with neurodevelopmental outcomes.
Keywords Basal Ganglia/diagnostic imaging/growth & developmentBrain/diagnostic imaging/growth & developmentCerebellum/diagnostic imaging/growth & developmentChild Development/physiologyDiffusion Magnetic Resonance ImagingEnergy IntakeEnteral NutritionFemaleHumansInfantNewbornInfantPremature/growth & developmentMaleProspective StudiesRespirationArtificialRespiratory Tract Diseases/therapyWhite Matter/diagnostic imaging/growth & development
PMID: 29440285
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Research group L'imagerie cérébrale (184)
Swiss National Science Foundation: 33CM30-124101
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SCHNEIDER, Juliane et al. Nutrient Intake in the First Two Weeks of Life and Brain Growth in Preterm Neonates. In: Pediatrics, 2018, vol. 141, n° 3, p. e20172169. doi: 10.1542/peds.2017-2169 https://archive-ouverte.unige.ch/unige:128459

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Deposited on : 2020-01-08

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