en
Scientific article
Open access
English

The expression of heat shock genes during normal development in Drosophila melanogaster (heat shock/abundant transcripts/developmental regulation)

Published inMolecular and General Genetics, vol. 194, no. 1-2, p. 73-78
Publication date1984
Abstract

Drosophila melanogaster cells and tissues respond to heat shock by dramatically altering their pattern of transcription and translation, leading to the rapid synthesis of a small number of polypeptides, the heat shock proteins (hsps). By using cloned hsp DNA we have detected sequences complementary to heat shock genes in RNA prepared from non-heat-shocked animals of different developmental stages. Hsp 83 mRNA is present at high levels in all stages examined. Hsp 68 and 70 mRNAs are present at very low levels in most stages and at slightly higher concentration in pupae. Hsp 26 and 27 mRNAs are detected in embryos. Hsp 23, 26 and 27 mRNA are barely detectable in early third instar larvae but are major components of late third instar and early pupal RNA. Hsp 22 mRNA is also detected in early pupae. Later in development the levels of the small hsp mRNAs decrease but a further peak in abundance of hsp 26 and 27 mRNAs is found in mature adult females.

Keywords
  • Polypeptide
  • Developmental stage
  • Heat shock
  • Heat shock protein
  • Adult female
Funding
  • Swiss National Science Foundation - 3.079.81
Citation (ISO format)
MASON, Philip John, HALL, Lucinda M. C., GAUSZ, Janos. The expression of heat shock genes during normal development in <i>Drosophila melanogaster</i> (heat shock/abundant transcripts/developmental regulation). In: Molecular and General Genetics, 1984, vol. 194, n° 1-2, p. 73–78. doi: 10.1007/BF00383500
Main files (1)
Article (Published version)
accessLevelPublic
Identifiers
ISSN of the journal0026-8925
245views
152downloads

Technical informations

Creation12/17/2019 12:58:00 PM
First validation12/17/2019 12:58:00 PM
Update time03/15/2023 6:36:21 PM
Status update03/15/2023 6:36:21 PM
Last indexation01/17/2024 8:33:18 AM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack