• Home
  1. Home
  2. Parathyroid hormone and plasma phosphate are predictors of soluble α-klotho levels in adults of European descent
Scientific article
OA Policy
English

Parathyroid hormone and plasma phosphate are predictors of soluble α-klotho levels in adults of European descent

ContributorsDhayat, Nasser A; Pruijm, Menno; Ponte, Belen; Ackermann, Daniel; Leichtle, Alexander Benedikt; Devuyst, Olivier; Ehret, Georg Benedikt; Guessous, Idris; Pechere, Antoinette; Pastor, Johanne; Martin, Pierre-Yves; Burnier, Michel; Fiedler, Georg-Martin; Vogt, Bruno; Moe, Orson W; Bochud, Murielle; Fuster, Daniel G
Published inJournal of Clinical Endocrinology and Metabolism
Publication date2019
Abstract

α-klotho is an integral membrane protein, that serves as a co-receptor for fibroblast growth factor 23 (FGF23) in conjunction with cognate fibroblast growth factor receptors. Proteolytic cleavage sheds the ectodomain of α-klotho (soluble α-klotho) as an endocrine substance into blood, urine and cerebrospinal fluid.

Keywords
  • Parathyroid hormone
  • Phosphate
  • Soluble α-klotho
Affiliation entities
Research groups
Citation (ISO format)
DHAYAT, Nasser A et al. Parathyroid hormone and plasma phosphate are predictors of soluble α-klotho levels in adults of European descent. In: Journal of Clinical Endocrinology and Metabolism, 2019. doi: 10.1210/clinem/dgz232
Main files (1)
Article (Accepted version)
accessLevelPublic
Identifiers
Journal ISSN0021-972X
388views
214downloads

Technical informations

Creation29/11/2019 20:17:00
First validation29/11/2019 20:17:00
Update24/01/2025 13:52:10
Status update24/01/2025 13:52:10
Last indexation24/01/2025 13:55:57
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack