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A framework based on sulcal constraints to align preterm, infant and adult human brain images acquired in vivo and post mortem |
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Published in | Brain structure & function. 2018, vol. 223, no. 9, p. 4153-4168 | |
Abstract | Robust spatial alignment of post mortem data and in vivo MRI acquisitions from different ages, especially from the early developmental stages, into standard spaces is still a bottleneck hampering easy comparison with the mainstream neuroimaging results. In this paper, we test a landmark-based spatial normalization strategy as a framework for the seamless integration of any macroscopic dataset in the context of the Human Brain Project (HBP). This strategy stems from an approach called DISCO embedding sulcal constraints in a registration framework used to initialize DARTEL, the widely used spatial normalization approach proposed in the SPM software. We show that this strategy is efficient with a heterogeneous dataset including challenging data as preterm newborns, infants, post mortem histological data and a synthetic atlas computed from averaging the ICBM database, as well as more commonly studied data acquired in vivo in adults. We then describe some perspectives for a research program aiming at improving folding pattern matching for atlas inference in the context of the future HBP's portal. | |
Keywords | Adult — Aged — 80 and over — Algorithms — Atlases as Topic — Brain/anatomy & histology — Databases — Factual — Humans — Image Processing — Computer-Assisted — Infant — Newborn — Premature — Magnetic Resonance Imaging/methods — Middle Aged — Software | |
Identifiers | PMID: 30187191 | |
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Research group | L'imagerie cérébrale (184) | |
Projects | European Commission: HBP SGA2 European Commission: HBP SGA1 European Commission: HBP | |
Citation (ISO format) | LEBENBERG, J et al. A framework based on sulcal constraints to align preterm, infant and adult human brain images acquired in vivo and post mortem. In: Brain Structure and Function, 2018, vol. 223, n° 9, p. 4153-4168. doi: 10.1007/s00429-018-1735-9 https://archive-ouverte.unige.ch/unige:128067 |