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Scientific article
English

A framework based on sulcal constraints to align preterm, infant and adult human brain images acquired in vivo and post mortem

Published inBrain Structure and Function, vol. 223, no. 9, p. 4153-4168
Publication date2018
Abstract

Robust spatial alignment of post mortem data and in vivo MRI acquisitions from different ages, especially from the early developmental stages, into standard spaces is still a bottleneck hampering easy comparison with the mainstream neuroimaging results. In this paper, we test a landmark-based spatial normalization strategy as a framework for the seamless integration of any macroscopic dataset in the context of the Human Brain Project (HBP). This strategy stems from an approach called DISCO embedding sulcal constraints in a registration framework used to initialize DARTEL, the widely used spatial normalization approach proposed in the SPM software. We show that this strategy is efficient with a heterogeneous dataset including challenging data as preterm newborns, infants, post mortem histological data and a synthetic atlas computed from averaging the ICBM database, as well as more commonly studied data acquired in vivo in adults. We then describe some perspectives for a research program aiming at improving folding pattern matching for atlas inference in the context of the future HBP's portal.

Keywords
  • Adult
  • Aged
  • 80 and over
  • Algorithms
  • Atlases as Topic
  • Brain/anatomy & histology
  • Databases
  • Factual
  • Humans
  • Image Processing
  • Computer-Assisted
  • Infant
  • Newborn
  • Premature
  • Magnetic Resonance Imaging/methods
  • Middle Aged
  • Software
Funding
  • European Commission - Human Brain Project Specific Grant Agreement 2 [785907]
  • European Commission - Human Brain Project Specific Grant Agreement 1 [720270]
  • European Commission - The Human Brain Project [604102]
Citation (ISO format)
LEBENBERG, J et al. A framework based on sulcal constraints to align preterm, infant and adult human brain images acquired in vivo and post mortem. In: Brain Structure and Function, 2018, vol. 223, n° 9, p. 4153–4168. doi: 10.1007/s00429-018-1735-9
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal1863-2653
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