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Title

Rare coding variants associated with blood pressure variation in 15 914 individuals of African ancestry

Authors
Nandakumar, Priyanka
Lee, Dongwon
Richard, Melissa A
Tekola-Ayele, Fasil
Tayo, Bamidele O
Ware, Erin
Sung, Yun J
Salako, Babatunde
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Published in Journal of Hypertension. 2017, vol. 35, no. 7, p. 1381-1389
Abstract Hypertension is a major risk factor for all cardiovascular diseases, especially among African Americans. This study focuses on identifying specific blood pressure (BP) genes using 15 914 individuals of African ancestry from eight cohorts (Africa America Diabetes Mellitus, Atherosclerosis Risk in Communities Study, Coronary Artery Risk Development in young Adults, Genetics Network, Genetic Epidemiology Network of Arteriopathy, Howard University Family Study, Hypertension Genetic Epidemiology Network, and Loyola University Chicago Cohort) to further genetic findings in this population which has generally been underrepresented in BP studies.
Keywords African Continental Ancestry Group/geneticsBlood Pressure/geneticsCardiovascular Diseases/geneticsCohort StudiesExomeGenetic VariationGenotypeHumansHypertension/geneticsRisk Factors
Identifiers
PMID: 28234671
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Research group Traits génétiques complexes (901)
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NANDAKUMAR, Priyanka et al. Rare coding variants associated with blood pressure variation in 15 914 individuals of African ancestry. In: Journal of Hypertension, 2017, vol. 35, n° 7, p. 1381-1389. doi: 10.1097/HJH.0000000000001319 https://archive-ouverte.unige.ch/unige:127659

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Deposited on : 2019-12-10

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