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Title

Appearance of a chromatin protein during the erythroid differentiation of Friend virus-transformed cells

Authors
Keppel, France
Eisen, Harvey
Published in Proceedings of the National Academy of Sciences. 1977, vol. 74, no. 2, p. 653-656
Abstract Chromatin proteins from erythroleukemia cells transformed by Friend virus were analyzed by sodium dodecyl sulfate/polyacrylamide gel electrophoresis. A new chromosomal protein, apparent molecular weight 25,000, was shown to appear during erythroid differentiation of the cells induced by dimethyl sulfoxide or hexamethylenebisacetamide. This protein is tightly bound to the chromatin and does not appear to be related to any of the known histones. It is also demonstrated that this protein is not induced in a dimethyl sulfoxide-resistant variant of these cells.
Keywords Nonhistone proteinsDimethyl sulfoxideErythroleukemia cellsHistones
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KEPPEL, France, ALLET, Bernard, EISEN, Harvey. Appearance of a chromatin protein during the erythroid differentiation of Friend virus-transformed cells. In: Proceedings of the National Academy of Sciences, 1977, vol. 74, n° 2, p. 653-656. doi: 10.1073/pnas.74.2.653 https://archive-ouverte.unige.ch/unige:127553

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Deposited on : 2019-12-06

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