Pressurized intraperitoneal aerosol chemotherapy (PIPAC) in combination with standard of care chemotherapy in primarily untreated chemo naïve upper gi-adenocarcinomas with peritoneal seeding - a phase II/III trial of the AIO/CAOGI/ACO

Goetze, Thorsten Oliver; Al-Batran, Salah-Eddin; Pabst, Urs; Reymond, Marc; Tempfer, Clemens; Bechstein, Wolf O; Bankstahl, Ulli; Gockel, Ines; Königsrainer, Alfred; Kraus, Thomas; Moenig, Stefan Paul; Rau, Beate; Schwarzbach, Matthias; Piso, Pompiliu

doi:10.1515/pp-2018-0113

Scientific article

Open access

English

Pressurized intraperitoneal aerosol chemotherapy (PIPAC) in combination with standard of care chemotherapy in primarily untreated chemo naïve upper gi-adenocarcinomas with peritoneal seeding - a phase II/III trial of the AIO/CAOGI/ACO

ContributorsGoetze, Thorsten Oliver; Al-Batran, Salah-Eddin; Pabst, Urs; Reymond, Marc; Tempfer, Clemens; Bechstein, Wolf O; Bankstahl, Ulli; Gockel, Ines; Königsrainer, Alfred; Kraus, Thomas; Moenig, Stefan Paul; Rau, Beate; Schwarzbach, Matthias; Piso, Pompiliu

Published inPleura and Peritoneum, vol. 3, no. 2, 20180113

Publication date2018

Abstract

Peritoneal metastasis is a common and dismal evolution of several gastrointestinal (GI) tumors, including gastric, colorectal, hepatobiliary, pancreatic, and other cancers. The therapy of peritoneal metastasis is largely palliative; with the aim of prolonging life and preserving its quality. In the meantime, a significant pharmacological advantage of intraperitoneal chemotherapy was documented in the preclinical model, and numerous clinical studies have delivered promising clinical results.

Keywords

Intraperitoneal therapy
Peritoneal carcinomatosis
Pressurized intraperitoneal aerosol chemotherapy (PIPAC)
Upper gastrointestinal cancer.

Affiliation

Faculté de médecine / Section de médecine clinique / Département de chirurgie

Research group

Transplantation et hépatologie (905)

Citation (ISO format)

GOETZE, Thorsten Oliver et al. Pressurized intraperitoneal aerosol chemotherapy (PIPAC) in combination with standard of care chemotherapy in primarily untreated chemo naïve upper gi-adenocarcinomas with peritoneal seeding - a phase II/III trial of the AIO/CAOGI/ACO. In: Pleura and Peritoneum, 2018, vol. 3, n° 2, p. 20180113. doi: 10.1515/pp-2018-0113